Long-term characterization of activated microglia/macrophages facilitating the development of experimental brain metastasis through intravital microscopic imaging

Long-term characterization of activated microglia/macrophages facilitating the development of experimental brain metastasis through intravital microscopic imaging

Abstract Background Microglia/macrophages (M/Ms) with multiple functions derived from distinct activation states are key surveillants maintaining brain homeostasis. However, their activation status and role during the brain metastasis of malignant tumors have been poorly characterized. Methods Heter...

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Bibliographic Details
Main Authors: Sha Qiao, Yuan Qian, Guoqiang Xu, Qingming Luo, Zhihong Zhang
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Neuroinflammation
Subjects:
Microglia/macrophage
Melanoma brain metastasis
Activation
Intravital imaging
MMP3
Online Access:http://link.springer.com/article/10.1186/s12974-018-1389-9

Internet

http://link.springer.com/article/10.1186/s12974-018-1389-9

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