Impact of glycosylation and length of RBD of SARS-CoV-2 S protein on the immunogenicity of RBD protein vaccines
Objective To analyze the impact of deglycosylation and length of RBD of SARS-CoV-2 S protein on the immunogenicity. Methods Based on the RBD of the SARS-CoV-2 S protein, three N-glycosylated residues (N331, N343, N360) in the 220 amino acid RBD (aa.331-550) were respectively mutated, and trimeriza...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2020-12-01
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| Series: | Jichu yixue yu linchuang |
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| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a201045.pdf |