Upregulation of IFNɣ-mediated chemokines dominate the immune transcriptome of muscle-invasive urothelial carcinoma
Abstract Tumor inflammation is prognostically significant in high-grade muscle-invasive bladder cancer (MIBC). However, the underlying mechanisms remain elusive. To identify inflammation-associated immune gene expression patterns, we performed transcriptomic profiling of 40 MIBC archival tumors usin...
Main Authors: | Ekaterina Olkhov-Mitsel, Anjelica Hodgson, Stan K. Liu, Danny Vesprini, Jane Bayani, John M. S. Bartlett, Bin Xu, Michelle R. Downes |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-04678-7 |
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