Acetyl Co-A Carboxylase Inhibition Halts Hyperglycemia Induced Upregulation of De Novo Lipogenesis in Podocytes and Proximal Tubular Cells

The effect of glycemic stress on de novo lipogenesis (DNL) in podocytes and tubular epithelial cells is understudied. This study is aimed (A) to show the effect of glycemic stress on DNL, and (B) to assess the effect of acetyl-Co A (ACC) inhibition on halting upregulation of DNL, on the expression o...

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Bibliographic Details
Main Authors: Pradeep Kayampilly, Nancy Roeser, Thekkelnaycke M Rajendiran, Subramaniam Pennathur, Farsad Afshinnia
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/10/940