CFTR interacts with Hsp90 and regulates the phosphorylation of AKT and ERK1/2 in colorectal cancer cells

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CF cells and tissues exhibit various mitochondrial abnormalities. However, the underlying molecular mechanisms remain elusive. Here, we examined the mechanisms through which CFTR regul...

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Bibliographic Details
Main Authors: Kaisheng Liu, Hongtao Jin, Yaomin Guo, Ying Liu, Yong Wan, Pan Zhao, Zhifan Zhou, Jianhong Wang, Maolin Wang, Chang Zou, Weiqing Wu, Zhiqiang Cheng, Yong Dai
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12641