Transcriptome and Proteome Analysis in LUHMES Cells Overexpressing Alpha-Synuclein

Transcriptome and Proteome Analysis in LUHMES Cells Overexpressing Alpha-Synuclein

LUHMES cells share many characteristics with human dopaminergic neurons in the substantia nigra, the cells, the demise of which is responsible for the motor symptoms in Parkinson's disease (PD). LUHMES cells can, therefore, be used bona fide as a model to study pathophysiological processes invo...

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Bibliographic Details
Main Authors: Matthias Höllerhage, Markus Stepath, Michael Kohl, Kathy Pfeiffer, Oscar Wing ho Chua, Linghan Duan, Franziska Hopfner, Martin Eisenacher, Katrin Marcus, Günter U. Höglinger
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Neurology
Subjects:
Parkinson's disease
alpha-synuclein
transcriptome
proteome
vesicular transport
synapse
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.787059/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2022.787059/full

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