Personalized Medicine to Improve Treatment of Dopa-Responsive Dystonia—A Focus on Tyrosine Hydroxylase Deficiency

Personalized Medicine to Improve Treatment of Dopa-Responsive Dystonia—A Focus on Tyrosine Hydroxylase Deficiency

Dopa-responsive dystonia (DRD) is a rare movement disorder associated with defective dopamine synthesis. This impairment may be due to the fact of a deficiency in GTP cyclohydrolase I (GTPCHI, <i>GCH1</i> gene), sepiapterin reductase (SR), tyrosine hydroxylase (TH), or 6-pyruvoyl tetrahy...

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Bibliographic Details
Main Authors: Gyrid Nygaard, Peter D. Szigetvari, Ann Kari Grindheim, Peter Ruoff, Aurora Martinez, Jan Haavik, Rune Kleppe, Marte I. Flydal
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Journal of Personalized Medicine
Subjects:
tyrosine hydroxylase
dopamine
dopa-responsive dystonia
dystonia
neurometabolic disorders
personalized medicine
Online Access:https://www.mdpi.com/2075-4426/11/11/1186

Internet

https://www.mdpi.com/2075-4426/11/11/1186

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