Translational regulation of specific mRNAs controls feedback inhibition and survival during macrophage activation.

For a rapid induction and efficient resolution of the inflammatory response, gene expression in cells of the immune system is tightly regulated at the transcriptional and post-transcriptional level. The control of mRNA translation has emerged as an important determinant of protein levels, yet its ro...

Полное описание

Библиографические подробности
Главные авторы: Johanna Schott, Sonja Reitter, Janine Philipp, Katharina Haneke, Heiner Schäfer, Georg Stoecklin
Формат: Статья
Язык:English
Опубликовано: Public Library of Science (PLoS) 2014-06-01
Серии:PLoS Genetics
Online-ссылка:http://europepmc.org/articles/PMC4063670?pdf=render