Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane

Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane

The flavoprotein kynurenine 3-monooxygenase (KMO) is localised to the outer mitochondrial membrane and catalyses the synthesis of 3-hydroxykynurenine from L-kynurenine, a key step in the kynurenine pathway (KP) of tryptophan degradation. Perturbation of KP metabolism due to inflammation has long bee...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Aisha M. Swaih, Carlo Breda, Korrapati V. Sathyasaikumar, Natalie Allcock, Mary E. W. Collier, Robert P. Mason, Adam Feasby, Federico Herrera, Tiago F. Outeiro, Robert Schwarcz, Mariaelena Repici, Flaviano Giorgini
التنسيق: مقال
اللغة:English
منشور في: MDPI AG 2022-09-01
سلاسل:Biomedicines
الموضوعات:
kynurenine 3-monooxygenase
Huntington’s disease
huntingtin
mitochondria
BiFC
live cell imaging
الوصول للمادة أونلاين:https://www.mdpi.com/2227-9059/10/9/2294

الانترنت

https://www.mdpi.com/2227-9059/10/9/2294

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