Dandelion extract inhibits triple-negative breast cancer cell proliferation by interfering with glycerophospholipids and unsaturated fatty acids metabolism

Dandelion extract inhibits triple-negative breast cancer cell proliferation by interfering with glycerophospholipids and unsaturated fatty acids metabolism

Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype with limited treatment options and a poor prognosis. TNBC exists widely reprogrammed lipid metabolism, and its metabolic-associated proteins and oncometabolites are promising as potential therapeutic targets. Dandelion...

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Bibliographic Details
Main Authors: Shan Wang, Hui-feng Hao, Yan-na Jiao, Jia-lei Fu, Zheng-wang Guo, Yang Guo, Yuan Yuan, Ping-ping Li, Shu-yan Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
triple-negative breast cancer
dandelion extract
multi-omics
glycerophospholipid metabolism
choline kinase α
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.942996/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.942996/full

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