Insights into the NAD+ biosynthesis pathways involved during meiotic maturation and spindle formation in porcine oocytes

Treatments that elevate NAD+ levels have been found to improve oocyte quality in mice, cattle, and pigs, suggesting that NAD+ is vital during oocyte maturation. This study aimed to examine the influence of different NAD+ biosynthetic pathways on oocyte quality by inhibiting key enzymes. Porcine oocy...

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Bibliographic Details
Main Authors: Charley-Lea POLLARD, Ashleigh YOUNAN, Aleona SWEGEN, Zamira GIBB, Christopher G. GRUPEN
Format: Article
Language:English
Published: The Society for Reproduction and Development 2022-03-01
Series:The Journal of Reproduction and Development
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jrd/68/3/68_2021-130/_pdf/-char/en