Lights and shadows on the use of metformin in pregnancy: from the preconception phase to breastfeeding and beyond

Lights and shadows on the use of metformin in pregnancy: from the preconception phase to breastfeeding and beyond

During pregnancy, the complex hormonal changes lead to a progressive decrease of insulin sensitivity that can drive the onset of gestational diabetes (GDM) or worsen an already-known condition of insulin resistance like type 2 diabetes, polycystic ovarian syndrome (PCOS), and obesity, with complicat...

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Bibliographic Details
Main Authors: Giulia Tosti, Annarita Barberio, Linda Tartaglione, Alessandro Rizzi, Mauro Di Leo, Luca Viti, Angelo Sirico, Sara De Carolis, Alfredo Pontecorvi, Antonio Lanzone, Dario Pitocco
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Endocrinology
Subjects:
gestational diabetes
insulin resistance
pregnancy
metformin
offspring
fertilization
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1176623/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1176623/full

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