Recent Advances in Chromatin Mechanisms Controlling Pancreatic Carcinogenesis
Pancreatic ductal adenocarcinoma has a heterogeneous genetic landscape, marked by frequent mutation of KRAS, CDKN2A, TP53, and SMAD4, resulting in poor responses to conventional therapeutic regimens. Over the past decade, increased understanding of the genetic underpinnings of this lethal cancer has...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2018-06-01
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| Series: | Epigenomes |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2075-4655/2/2/11 |