Roles of cancer-associated fibroblasts (CAFs) in anti- PD-1/PD-L1 immunotherapy for solid cancers

Abstract In recent years, breakthroughs have been made in tumor immunotherapy. However, tumor immunotherapy, particularly anti-PD-1/PD-L1 immune checkpoint inhibitors, is effective in only a small percentage of patients in solid cancer. How to improve the efficiency of cancer immunotherapy is an urg...

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Bibliographic Details
Main Authors: Liping Pei, Yang Liu, Lin Liu, Shuochen Gao, Xueyan Gao, Yudi Feng, Zhenqiang Sun, Yan Zhang, Chengzeng Wang
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Molecular Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12943-023-01731-z