Accurate classification of pulmonary nodules by a combined model of clinical, imaging, and cell-free DNA methylation biomarkers: a model development and external validation study

Summary: Background: There is an unmet clinical need for accurate non-invasive tests to facilitate the early diagnosis of lung cancer. We propose a combined model of clinical, imaging, and cell-free DNA methylation biomarkers that aims to improve the classification of pulmonary nodules. Methods: We...

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Bibliographic Details
Main Authors: Jianxing He, ProfMD, Bo Wang, BS, Jinsheng Tao, MSc, Qin Liu, MM, Minhua Peng, PhD, Shan Xiong, MD, Jianfu Li, MD, Bo Cheng, MD, Caichen Li, MD, Shunjun Jiang, MD, Xiangcheng Qiu, BS, Yang Yang, MB, Zhujia Ye, PhD, Fanrui Zeng, MD, Jian Zhang, ProfMD, Dan Liu, ProfMD, Weimin Li, ProfMD, Zhiwei Chen, PhD, Qingsi Zeng, ProfMD, Jian-Bing Fan, ProfPhD, Wenhua Liang, ProfMD
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:The Lancet: Digital Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2589750023001255