Prostaglandin F2α analogue, bimatoprost ameliorates colistin-induced nephrotoxicity

Prostaglandin F2α analogue, bimatoprost ameliorates colistin-induced nephrotoxicity

Colistin (polymyxin E) is an antibiotic that is effective against multidrug-resistant gram-negative bacteria. However, the high incidence of nephrotoxicity caused by colistin limits its clinical use. To identify compounds that might ameliorate colistin-induced nephrotoxicity, we obtained 1707 compou...

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Bibliographic Details
Main Authors: Lina Joo, Hye Yun Jeong, Dong Hyuck Bae, Joo Hyun Jee, Woo Hee Choi, Hye-Youn Kim, Sejoong Kim, Dong-Ho Yang, Heon Yung Gee, SeongGyeong Jeon, Yun-Gil Roh, Jongman Yoo
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Bimatoprost
Colistin
Nephrotoxicity
Drug repurposing
Oxidative stress
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223012441

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http://www.sciencedirect.com/science/article/pii/S0753332223012441

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