The NKCC1 antagonist bumetanide mitigates interneuronopathy associated with ethanol exposure in utero

Prenatal exposure to ethanol induces aberrant tangential migration of corticopetal GABAergic interneurons, and long-term alterations in the form and function of the prefrontal cortex. We have hypothesized that interneuronopathy contributes significantly to the pathoetiology of fetal alcohol spectrum...

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Bibliographic Details
Main Authors: Alexander GJ Skorput, Stephanie M Lee, Pamela WL Yeh, Hermes H Yeh
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/48648