Allogeneic CD20‐targeted γδ T cells exhibit innate and adaptive antitumor activities in preclinical B‐cell lymphoma models

Allogeneic CD20‐targeted γδ T cells exhibit innate and adaptive antitumor activities in preclinical B‐cell lymphoma models

Abstract Objectives Autologous chimeric antigen receptor (CAR) αβ T‐cell therapies have demonstrated remarkable antitumor efficacy in patients with haematological malignancies; however, not all eligible cancer patients receive clinical benefit. Emerging strategies to improve patient access and clini...

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Bibliographic Details
Main Authors: Kevin P Nishimoto, Taylor Barca, Aruna Azameera, Amani Makkouk, Jason M Romero, Lu Bai, Mary M Brodey, Jackie Kennedy‐Wilde, Hui Shao, Stephanie Papaioannou, Amy Doan, Cynthia Masri, Ngoc T Hoang, Hayden Tessman, Vidhya Dhevi Ramanathan, Ana Giner‐Rubio, Frank Delfino, Kriti Sharma, Kevin Bray, Matthew Hoopes, Daulet Satpayev, Ranjita Sengupta, Marissa Herrman, Stewart E Abbot, Blake T Aftab, Zili An, Swapna Panuganti, Sandra M Hayes
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Clinical & Translational Immunology
Subjects:
adoptive cell therapy
B‐cell lymphoma
CD20
chimeric antigen receptor
γδ T cells
Online Access:https://doi.org/10.1002/cti2.1373

Internet

https://doi.org/10.1002/cti2.1373

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