High-throughput protein characterization by complementation using DNA barcoded fragment libraries

High-throughput protein characterization by complementation using DNA barcoded fragment libraries

Abstract Our ability to predict, control, or design biological function is fundamentally limited by poorly annotated gene function. This can be particularly challenging in non-model systems. Accordingly, there is motivation for new high-throughput methods for accurate functional annotation. Here, we...

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Bibliographic Details
Main Authors: Bradley W Biggs, Morgan N Price, Dexter Lai, Jasmine Escobedo, Yuridia Fortanel, Yolanda Y Huang, Kyoungmin Kim, Valentine V Trotter, Jennifer V Kuehl, Lauren M Lui, Romy Chakraborty, Adam M Deutschbauer, Adam P Arkin
Format: Article
Language:English
Published: Springer Nature 2024-10-01
Series:Molecular Systems Biology
Subjects:
DNA Barcoding
Functional Genomics
High-throughput Characterization
Protein Annotation
Online Access:https://doi.org/10.1038/s44320-024-00068-z

Internet

https://doi.org/10.1038/s44320-024-00068-z

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