A semi-supervised Bayesian approach for simultaneous protein sub-cellular localisation assignment and novelty detection.

The cell is compartmentalised into complex micro-environments allowing an array of specialised biological processes to be carried out in synchrony. Determining a protein's sub-cellular localisation to one or more of these compartments can therefore be a first step in determining its function. H...

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Bibliographic Details
Main Authors: Oliver M Crook, Aikaterini Geladaki, Daniel J H Nightingale, Owen L Vennard, Kathryn S Lilley, Laurent Gatto, Paul D W Kirk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008288