Radiation combined with macrophage depletion promotes adaptive immunity and potentiates checkpoint blockade
Abstract Emerging evidence suggests a role for radiation in eliciting anti‐tumour immunity. We aimed to investigate the role of macrophages in modulating the immune response to radiation. Irradiation to murine tumours generated from colorectal (MC38) and pancreatic (KPC) cell lines induced colony‐st...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2018-12-01
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Series: | EMBO Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.15252/emmm.201809342 |