Lactadherin immunoblockade in small extracellular vesicles inhibits sEV-mediated increase of pro-metastatic capacities

Abstract Background Tumor-derived small extracellular vesicles (sEVs) can promote tumorigenic and metastatic capacities in less aggressive recipient cells mainly through the biomolecules in their cargo. However, despite recent advances, the specific molecules orchestrating these changes are not comp...

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Bibliographic Details
Main Authors: Eduardo Durán-Jara, Matías del Campo, Valentina Gutiérrez, Ignacio Wichmann, César Trigo, Marcelo Ezquer, Lorena Lobos-González
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Biological Research
Subjects:
Online Access:https://doi.org/10.1186/s40659-023-00477-8