A novel mechanosensitive channel controls osmoregulation, differentiation, and infectivity in Trypanosoma cruzi

A novel mechanosensitive channel controls osmoregulation, differentiation, and infectivity in Trypanosoma cruzi

The causative agent of Chagas disease undergoes drastic morphological and biochemical modifications as it passes between hosts and transitions from extracellular to intracellular stages. The osmotic and mechanical aspects of these cellular transformations are not understood. Here we identify and cha...

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Bibliographic Details
Main Authors: Noopur Dave, Ugur Cetiner, Daniel Arroyo, Joshua Fonbuena, Megna Tiwari, Patricia Barrera, Noelia Lander, Andriy Anishkin, Sergei Sukharev, Veronica Jimenez
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
mechanosensation
calcium
osmoregulation
Trypanosoma cruzi
CRISPR-Cas9
electrophysiology
Online Access:https://elifesciences.org/articles/67449

Internet

https://elifesciences.org/articles/67449

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