The role of cellular traction forces in deciphering nuclear mechanics
Abstract Cellular forces exerted on the extracellular matrix (ECM) during adhesion and migration under physiological and pathological conditions regulate not only the overall cell morphology but also nuclear deformation. Nuclear deformation can alter gene expression, integrity of the nuclear envelop...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS)
2022-09-01
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Series: | Biomaterials Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40824-022-00289-z |