Markers of neutrophil activation and extracellular traps formation are predictive of appendicitis in mice and humans: a pilot study

Abstract Appendicitis is one of the most frequent emergencies in pediatric surgery, yet current biomarkers for diagnosis are unspecific and have low predictive values. As neutrophils and extracellular traps (ETs) are an essential component of the immune defense against bacterial infections, and appe...

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Bibliographic Details
Main Authors: Michael Boettcher, Melina Esser, Julian Trah, Stefan Klohs, Nariman Mokhaberi, Julia Wenskus, Madgalena Trochimiuk, Birgit Appl, Konrad Reinshagen, Laia Pagerols Raluy, Michaela Klinke
Format: Article
Language:English
Published: Nature Portfolio 2020-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-74370-9