Elucidation of the Cellular Interactome of African Swine Fever Virus Fusion Proteins and Identification of Potential Therapeutic Targets

Elucidation of the Cellular Interactome of African Swine Fever Virus Fusion Proteins and Identification of Potential Therapeutic Targets

African swine fever virus (ASFV) encodes more than 150 proteins, most of them of unknown function. We used a high-throughput proteomic analysis to elucidate the interactome of four ASFV proteins, which potentially mediate a critical step of the infection cycle, the fusion and endosomal exit of the v...

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Bibliographic Details
Main Authors: Isabel García-Dorival, Miguel Ángel Cuesta-Geijo, Inmaculada Galindo, Ana del Puerto, Lucía Barrado-Gil, Jesús Urquiza, Covadonga Alonso
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Viruses
Subjects:
virus–host interaction
interactome
drug target
lipid metabolism enzymes
fusion proteins
African swine fever virus
Online Access:https://www.mdpi.com/1999-4915/15/5/1098

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https://www.mdpi.com/1999-4915/15/5/1098

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