Real-world evidence study finds no new-onset diabetes or drug-related hyperglycemia in Pompe disease patients treated with avalglucosidase alfa

Real-world evidence study finds no new-onset diabetes or drug-related hyperglycemia in Pompe disease patients treated with avalglucosidase alfa

Avalglucosidase alfa therapy for Pompe disease is diluted in dextrose 5% solution in water (D5W) for infusion, which raises questions about the potential for hyperglycemia or worsening diabetes. Using United States insurance claims data, we assessed the impact of biweekly infusions on hyperglycemia,...

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Bibliographic Details
Main Authors: Alexandra Dumitriu, Ann Lucas, Raffaella Colzani
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Molecular Genetics and Metabolism Reports
Subjects:
Avalglucosidase alfa
Pompe disease
Hyperglycemia
Diabetes mellitus
Insulin resistance
Prediabetes
Online Access:http://www.sciencedirect.com/science/article/pii/S221442692400017X

Internet

http://www.sciencedirect.com/science/article/pii/S221442692400017X

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