Head pleomorphic sarcoma showing murine double minute 2 amplification without a well‐differentiated liposarcoma component in a pediatric patient

Abstract Background Murine double minute 2 (MDM2) is an oncogene that inhibits p53, leading to decreased apoptosis. Sarcomas showing MDM2 amplification are rare among pediatric patients. Case A 14‐year‐old boy presented with pleomorphic sarcoma of the head showing MDM2 amplification without a well‐d...

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Bibliographic Details
Main Authors: Mitsuko Akaihata, Ikuko Takahashi, Yuko Kakuda, Takuya Kawata, Takashi Mukaigawa, Testuro Onitsuka, Shigeyuki Murayama, Yuji Ishida
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Cancer Reports
Subjects:
Online Access:https://doi.org/10.1002/cnr2.1774