SNP-SNP Interaction in Genes Encoding PD-1/PD-L1 Axis as a Potential Risk Factor for Clear Cell Renal Cell Carcinoma

SNP-SNP Interaction in Genes Encoding PD-1/PD-L1 Axis as a Potential Risk Factor for Clear Cell Renal Cell Carcinoma

PD-1/PD-L1 axis plays an important role in maintaining homeostasis and prevention from autoimmunity; however, in the tumor microenvironment, PD-1/PD-L1 interaction is responsible for the evasion of immune surveillance by tumor cells. We therefore hypothesized that single nucleotide polymorphisms (SN...

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Bibliographic Details
Main Authors: Marta Wagner, Krzysztof Tupikowski, Monika Jasek, Anna Tomkiewicz, Agata Witkowicz, Kuba Ptaszkowski, Pawel Karpinski, Romuald Zdrojowy, Agnieszka Halon, Lidia Karabon
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
clear cell renal cell carcinoma
PD-1 (PDCD1)
PD-L1
single nucleotide polymorphism
Online Access:https://www.mdpi.com/2072-6694/12/12/3521

Internet

https://www.mdpi.com/2072-6694/12/12/3521

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