Multicomponent depolymerization of actin filament pointed ends by cofilin and cyclase-associated protein depends upon filament age
Intracellular actin networks assemble through the addition of ATP-actin subunits at the growing barbed ends of actin filaments. This is followed by “aging” of the filament via ATP hydrolysis and subsequent phosphate release. Aged ADP-actin subunits thus “treadmill” through the filament before being...
Principais autores: | , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Elsevier
2024-06-01
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coleção: | European Journal of Cell Biology |
Assuntos: | |
Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S0171933524000402 |