Multicomponent depolymerization of actin filament pointed ends by cofilin and cyclase-associated protein depends upon filament age

Intracellular actin networks assemble through the addition of ATP-actin subunits at the growing barbed ends of actin filaments. This is followed by “aging” of the filament via ATP hydrolysis and subsequent phosphate release. Aged ADP-actin subunits thus “treadmill” through the filament before being...

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Detalhes bibliográficos
Principais autores: Ekram M. Towsif, Blake Andrew Miller, Heidi Ulrichs, Shashank Shekhar
Formato: Artigo
Idioma:English
Publicado em: Elsevier 2024-06-01
coleção:European Journal of Cell Biology
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0171933524000402