Physapruin A Enhances DNA Damage and Inhibits DNA Repair to Suppress Oral Cancer Cell Proliferation

Physapruin A Enhances DNA Damage and Inhibits DNA Repair to Suppress Oral Cancer Cell Proliferation

The selective antiproliferation to oral cancer cells of <i>Physalis peruviana</i>-derived physapruin A (PHA) is rarely reported. Either drug-induced apoptosis and DNA damage or DNA repair suppression may effectively inhibit cancer cell proliferation. This study examined the selective ant...

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Bibliographic Details
Main Authors: Tzu-Jung Yu, Ching-Yu Yen, Yuan-Bin Cheng, Chia-Hung Yen, Jiiang-Huei Jeng, Jen-Yang Tang, Hsueh-Wei Chang
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
withanolides
oral cancer
antiproliferation
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/23/16/8839

Internet

https://www.mdpi.com/1422-0067/23/16/8839

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