Ethanol Induces Microglial Cell Death via the NOX/ROS/PARP/TRPM2 Signalling Pathway

Ethanol Induces Microglial Cell Death via the NOX/ROS/PARP/TRPM2 Signalling Pathway

Microglial cells are the primary immune cell resident in the brain. Growing evidence indicates that microglial cells play a prominent role in alcohol-induced brain pathologies. However, alcohol-induced effects on microglial cells and the underlying mechanisms are not fully understood, and evidence e...

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Bibliographic Details
Main Authors: Muhammad Syahreel Azhad Sha’fie, Sharani Rathakrishnan, Iffa Nadhira Hazanol, Mohd Haziq Izzazuddin Dali, Mohd Ezuan Khayat, Syahida Ahmad, Yazmin Hussin, Noorjahan Banu Alitheen, Lin-Hua Jiang, Sharifah Alawieyah Syed Mortadza
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Antioxidants
Subjects:
alcoholism
microglia
cell death
ROS
oxidative stress
PARP
Online Access:https://www.mdpi.com/2076-3921/9/12/1253

Internet

https://www.mdpi.com/2076-3921/9/12/1253

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