Analysis of the intracellular traffic of IgG in the context of Down syndrome (trisomy 21)

Abstract Persons with Down syndrome (DS, trisomy 21) have widespread cellular protein trafficking defects. There is a paucity of data describing the intracellular transport of IgG in the context of endosomal-lysosomal alterations linked to trisomy 21. In this study, we analyzed the intracellular tra...

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Bibliographic Details
Main Authors: R. B. Cejas, M. Tamaño-Blanco, J. G. Blanco
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90469-z