Synthesis, Crystal Structure, and Biological Evaluation of a Series of Phloretin Derivatives

A one-step synthesis of phloretin derivatives 2–11 from phloretin in good to excellent yields is reported. Their structures were characterized by 1H-NMR, 13C-NMR and MS, and the structures of 8 and 11 were determined by X-ray diffraction analysis. A mechanism for the formation of 9–11 is proposed. C...

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Bibliographic Details
Main Authors: Li Wang, Zheng-Wei Li, Wei Zhang, Rui Xu, Fei Gao, Yang-Feng Liu, Ya-Jun Li
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/10/16447