The Use of Baclofen as a Treatment for Alcohol Use Disorder: A Clinical Practice Perspective

The Use of Baclofen as a Treatment for Alcohol Use Disorder: A Clinical Practice Perspective

Alcohol use disorder (AUD) is a brain disorder associated with high rates of mortality and morbidity worldwide. Baclofen, a selective gamma-aminobutyric acid-B (GABA-B) receptor agonist, has emerged as a promising drug for AUD. The use of this drug remains controversial, in part due to uncertainty r...

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Bibliographic Details
Main Authors: Renaud de Beaurepaire, Julia M. A. Sinclair, Mathis Heydtmann, Giovanni Addolorato, Henri-Jean Aubin, Esther M. Beraha, Fabio Caputo, Jonathan D. Chick, Patrick de La Selle, Nicolas Franchitto, James C. Garbutt, Paul S. Haber, Philippe Jaury, Anne R. Lingford-Hughes, Kirsten C. Morley, Christian A. Müller, Lynn Owens, Adam Pastor, Louise M. Paterson, Fanny Pélissier, Benjamin Rolland, Amanda Stafford, Andrew Thompson, Wim van den Brink, Lorenzo Leggio, Roberta Agabio
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Psychiatry
Subjects:
GABA-B
baclofen
alcohol use disorder
efficacy
safety
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00708/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2018.00708/full

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