Intracellular glutathione pools are heterogeneously concentrated

Intracellular glutathione pools are heterogeneously concentrated

Glutathione is present in millimolar concentrations in the cell, but its relative distribution among cellular compartments remains elusive. We have chosen the endoplasmic reticulum (ER) as an example organelle to study compartment-specific glutathione levels. Using a glutaredoxin sensor (sCGrx1pER),...

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Bibliographic Details
Main Authors: Davide Montero, Christine Tachibana, Jakob Rahr Winther, Christian Appenzeller-Herzog
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
Endoplasmic reticulum
Glutathione
Glutaredoxin
Redox compartmentalization
Redox Homeostasis
Reduction potential
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231713000748

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http://www.sciencedirect.com/science/article/pii/S2213231713000748

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