EZH2 Methyltransferase and H3K27 Methylation in Breast Cancer

<p>Histone modifications are thought to control the regulation of genetic programs in normal physiology and cancer. Methylation (mono-, di-, and tri-methylation) on histone H3 lysine (K) 27 induces transcriptional repression, and thereby participates in controlling gene expression patterns. En...

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Bibliographic Details
Main Author: Kyung Hyun Yoo, Lothar Hennighausen
Format: Article
Language:English
Published: Ivyspring International Publisher 2012-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v08p0059.htm