Tissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox

Tissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox

Abstract Background Retinal pigment epithelium (RPE) cell therapy is a promising way to treat many retinal diseases. However, obtaining transplantable RPE cells is time-consuming and less effective. This study aimed to develop novel strategies for generating engineered RPE patches with physiological...

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Bibliographic Details
Main Authors: Wenxuan Wang, Tingting Yang, Sihui Chen, Liying Liang, Yingxin Wang, Yin Ding, Wei Xiong, Xiuhong Ye, Yonglong Guo, Shuhao Shen, Hang Chen, Jiansu Chen
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Biological Engineering
Subjects:
Retinal pigment epithelium
TGF-β
ROCK
Spheroid
Collagen vitrigel scaffold
Tissue engineering
Online Access:https://doi.org/10.1186/s13036-024-00405-8

Internet

https://doi.org/10.1186/s13036-024-00405-8

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