Compatibility of Caco-2 cells with Simulated Intestinal Fluid-Predicting Permeability
The Caco-2 cell model is considered the gold standard when analysing drug permeability and risk-assessing bioavailability. The use of Simulated Intestinal Fluid (SIF) as a tool in the Caco-2 models is beneficial as this generates a more physiologically relevant model. Existing work using biorelevan...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
University of Huddersfield Press
2023-12-01
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Series: | British Journal of Pharmacy |
Subjects: | |
Online Access: | https://www.bjpharm.org.uk/article/1403/galley/1051/view/ |