Compatibility of Caco-2 cells with Simulated Intestinal Fluid-Predicting Permeability

The Caco-2 cell model is considered the gold standard when analysing drug permeability and risk-assessing bioavailability. The use of Simulated Intestinal Fluid (SIF) as a tool in the Caco-2 models is beneficial as this generates a more physiologically relevant model. Existing work using biorelevan...

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Bibliographic Details
Main Authors: Erin Seonaid Campbell, Hannah Batchelor, James Matthew Butler, Ibrahim Khadra, Nena Minstry, Konstantinos Stamatopoulos
Format: Article
Language:English
Published: University of Huddersfield Press 2023-12-01
Series:British Journal of Pharmacy
Subjects:
Online Access:https://www.bjpharm.org.uk/article/1403/galley/1051/view/