Racotumomab: An Anti-Idiotype Vaccine Related to N-Glycolyl-Containing-Gangliosides. Preclinical and Clinical Data.
Neu-glycolyl (NeuGc) containing gangliosides are attractive targets for immunotherapy with anti-idiotype mAbs, because these glycolipids are not normal components of the cytoplasmatic membrane in humans, but their expression has been demonstrated in several human malignant tumors. Racotumomab is an...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-10-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00150/full |