Ufmylation on UFBP1 alleviates non-alcoholic fatty liver disease by modulating hepatic endoplasmic reticulum stress

Abstract Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease characterized by lipid accumulation and endoplasmic reticulum (ER) stress, while effective therapies targeting the specific characteristics of NAFLD are limited. Ufmylation is a newly found post-translational modific...

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Bibliographic Details
Main Authors: Ziming Mao, Xiaowen Ma, Yu Jing, Minyan Shen, Xirui Ma, Jing Zhu, Huifang Liu, Guangya Zhang, Fengling Chen
Format: Article
Language:English
Published: Nature Publishing Group 2023-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06095-2