Adaptive laboratory evolution of antimicrobial resistance in bacteria for genetic and phenotypic analyses

Adaptive laboratory evolution of antimicrobial resistance in bacteria for genetic and phenotypic analyses

Summary: Adaptive laboratory evolution (ALE) of bacteria has the potential to provide many insights like revealing novel mechanisms of resistance and elucidating the impact of drug combinations and concentrations on AMR evolution. Here, we describe a step-by-step ALE protocol for the model bacterium...

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Bibliographic Details
Main Authors: Rhea Vinchhi, Chinmaya Jena, Nishad Matange
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:STAR Protocols
Subjects:
Genetics
Sequencing
Microbiology
Model Organisms
Evolutionary biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722008851

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http://www.sciencedirect.com/science/article/pii/S2666166722008851

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