Generation of Hepatocyte-Like Cells from Human Embryonic Stem Cells

Use of human hepatocytes for therapeutic and drug discovery applications is hampered by limited tissue source and the inability of hepatocytes to proliferate and maintain function long term in vitro. Human embryonic stem (hES) cells are immortal and pluripotent and may provide a cell source for func...

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Bibliographic Details
Main Authors: Lakshmi Rambhatla, Choy-Pik Chiu, Pratima Kundu, Yun Peng, Melissa K. Carpenter
Format: Article
Language:English
Published: SAGE Publishing 2003-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000003783985179