The effect of hydroxychloroquine on cholesterol synthesis depends on the profile of cholesterol metabolism. A controlled clinical study

Background and aims: Hydroxychloroquine (HCQ) has a variable effect on cholesterol synthesis. To clarify this, we assessed the effect of HCQ on the cholesterol-synthesis pathway in individuals with low and high cholesterol absorption efficiency. Method: A total of 53 acute myocardial infarction pati...

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Bibliographic Details
Main Authors: Piia Simonen, Lotta Ulander, Kari K. Eklund, Mikko Niemi, Janne T. Backman, Helena Gylling, Juha Sinisalo
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Atherosclerosis Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667089524000087