New Quinazolin-4(3H)-One Derivatives Incorporating Isoxazole Moiety as Antioxidant Agents: Synthesis, Structural Characterization, and Theoretical DFT Mechanistic Study

New Quinazolin-4(3H)-One Derivatives Incorporating Isoxazole Moiety as Antioxidant Agents: Synthesis, Structural Characterization, and Theoretical DFT Mechanistic Study

<b>Background</b>: This research centers on the development and spectroscopic characterization of new quinazolin-4(3H)-one-isoxazole derivatives (<b>5a–e</b>). The aim was to investigate the regioselectivity of the 1,3-dipolar cycloaddition involving arylnitriloxides and N-pr...

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Bibliographic Details
Main Authors: Yassine Rhazi, Riham Sghyar, Noemi Deak, Bouchra Es-Sounni, Bouchra Rossafi, Albert Soran, Mustapha Laghmari, Azize Arzine, Asmae Nakkabi, Khalil Hammani, Samir Chtita, Mohammed M. Alanazi, Gabriela Nemes, Mohamed El. Yazidi
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Pharmaceuticals
Subjects:
quinazolin-(3H)-one
isoxazole
DFT mechanistic study
antioxidant agents
Online Access:https://www.mdpi.com/1424-8247/17/10/1390

Internet

https://www.mdpi.com/1424-8247/17/10/1390

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