Isoliensinine from Cissampelos pariera rhizomes exhibits potential gametocytocidal and anti-malarial activities against Plasmodium falciparum clinical isolates

Isoliensinine from Cissampelos pariera rhizomes exhibits potential gametocytocidal and anti-malarial activities against Plasmodium falciparum clinical isolates

Abstract Background The unmet demand for effective malaria transmission-blocking agents targeting the transmissible stages of Plasmodium necessitates intensive discovery efforts. In this study, a bioactive bisbenzylisoquinoline (BBIQ), isoliensinine, from Cissampelos pariera (Menispermaceae) rhizome...

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Detalles Bibliográficos
Autores principales: Jackson M. Muema, James M. Mutunga, Meshack A. Obonyo, Merid N. Getahun, Ramadhan S. Mwakubambanya, Hoseah M. Akala, Agnes C. Cheruiyot, Redemptah A. Yeda, Dennis W. Juma, Ben Andagalu, Jaree L. Johnson, Amanda L. Roth, Joel L. Bargul
Formato: Artículo
Lenguaje:English
Publicado: BMC 2023-05-01
Colección:Malaria Journal
Materias:
Isoliensinine
Gametocytes
Plasmodium transmission-blocking
Cissampelos pariera
Malaria control
Natural product
Acceso en línea:https://doi.org/10.1186/s12936-023-04590-7

Internet

https://doi.org/10.1186/s12936-023-04590-7

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