Cardiomyocyte intercellular signalling increases oxidative stress and reprograms the global‐ and phospho‐proteome of cardiac fibroblasts

Abstract Pathological reprogramming of cardiomyocyte and fibroblast proteome landscapes drive the initiation and progression of cardiac fibrosis. Although the secretome of dysfunctional cardiomyocytes is emerging as an important driver of pathological fibroblast reprogramming, our understanding of t...

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Bibliographic Details
Main Authors: Bethany Claridge, Alin Rai, Jarmon G. Lees, Haoyun Fang, Shiang Y. Lim, David W. Greening
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Journal of Extracellular Biology
Subjects:
Online Access:https://doi.org/10.1002/jex2.125