Determination of the Duplicated <i>CYP2D6</i> Allele Using Real-Time PCR Signal: An Alternative Approach

Determination of the Duplicated <i>CYP2D6</i> Allele Using Real-Time PCR Signal: An Alternative Approach

<i>CYP2D6</i> duplication has important pharmacogenomic implications. Reflex testing with long-range PCR (LR-PCR) can resolve the genotype when a duplication and alleles with differing activity scores are detected. We evaluated whether visual inspection of plots from real-time-PCR-based...

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Bibliographic Details
Main Authors: Mazen A. Atiq, Sandra E. Peterson, Loralie J. Langman, Linnea M. Baudhuin, John L. Black, Ann M. Moyer
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Journal of Personalized Medicine
Subjects:
<i>CYP2D6</i>
real-time PCR
Sanger sequencing
pharmacogenomics
duplications
copy number variation
Online Access:https://www.mdpi.com/2075-4426/13/6/883

Internet

https://www.mdpi.com/2075-4426/13/6/883

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