A Hierarchical Cascade of Second Messengers Regulates <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Surface Behaviors

ABSTRACT  Biofilms are surface-attached multicellular communities. Using single-cell tracking microscopy, we showed that a pilY1 mutant of Pseudomonas aeruginosa is defective in early biofilm formation. We leveraged the observation that PilY1 protein levels increase on a surface to perform a genetic...

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Bibliographic Details
Main Authors: Yun Luo, Kun Zhao, Amy E. Baker, Sherry L. Kuchma, Kimberly A. Coggan, Matthew C. Wolfgang, Gerard C. L. Wong, George A. O’Toole
Format: Article
Language:English
Published: American Society for Microbiology 2015-02-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.02456-14