Pyroptosis-related genes regulate proliferation and invasion of pancreatic cancer and serve as the prognostic signature for modeling patient survival

Pyroptosis-related genes regulate proliferation and invasion of pancreatic cancer and serve as the prognostic signature for modeling patient survival

Abstract Objective Pancreatic ductal adenocarcinoma (PDAC) has high mortality and poor prognosis. Pyroptosis can influence the prognosis of patients by regulating the proliferation, invasion, and metastasis of cancer cells. However, the role of pyroptosis-related genes (PRGs) in PDAC remains unclear...

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Bibliographic Details
Main Authors: Wenjing Song, Zhicheng Liu, Kunlei Wang, Kai Tan, Anbang Zhao, Xinyin Li, Yufeng Yuan, Zhiyong Yang
Format: Article
Language:English
Published: Springer 2022-05-01
Series:Discover Oncology
Subjects:
Pyroptosis
CASP4
NLRP1
Pancreatic ductal adenocarcinoma
Gene signature
Prognosis
Online Access:https://doi.org/10.1007/s12672-022-00495-0

Internet

https://doi.org/10.1007/s12672-022-00495-0

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